Diabetes And Cardiovascular Disease Trial Involving Intensively Lower Blood Glucose Stopped For Risk Of Death
Diabetes And Cardiovascular Disease Trial Involving Intensively Lower Blood Glucose Stopped For Risk Of Death
NIH has stopped one treatment within the ACCORD study, a large, ongoing North American clinical trial of diabetes and cardiovascular disease, 18 months early due to safety concerns after review of available data, although the study will continue. In this trial of adults with type 2 diabetes at especially high risk for heart attack and stroke, the medical strategy to intensively lower blood glucose (sugar) below current recommendations increased the risk of death compared with a less-intensive standard treatment strategy.
Brain Circuitry That Drives Drug-seeking Compulsion Identified
In experiments with rats, researchers have identified the change in brain circuitry that drives development of a compulsion to seek drugs, even when that compulsion is self-destructive. The researchers demonstrated the function of the circuitry by selectively switching off drug-seeking in the animals. They said their findings show the key role of the brain region, known as the striatum, which is a region activated by reward.
Could Statins Prevent Cancer?
A new study evaluates the relationship between statin use and cancer incidence. ACS experts say more research is needed.
Treating Acne: Two Different Acid Peels Are Both Effective, Study Finds
Chemical peels using either alpha-hydroxy acid or beta-hydroxy acid are both highly effective in treating mild to moderately severe facial acne, researchers have found -- the first study to compare the two different types of acid peels as therapies for the skin disorder. Peels using beta-hydroxy acid (or BHA) had slightly fewer side effects and results that lasted a bit longer than did peels using alpha-hydroxy acid (or AHA), the study found.
Organic Solar Cells: Electricity From A Thin Film
Teams of researchers all over the world are working on the development of organic solar cells. Organic solar cells have good prospects for the future: They can be laid onto thin films, which makes them cheap to produce.
Managing Chronic Pain: When Does Morphine Become Less Effective?
Opioids, such as morphine, are effective and widely used drugs for the control of pain. However, tolerance to opioids can develop with repeated administration (that is, higher and higher doses of the drug are required to achieve the same level of pain relief).
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